You didn't give much info to go on. It would have been helpful if you provided the names of his wife and children, as it is I can only guess as to which family is the one you are looking for.
Wm. Cook 34
B. Cook 27 female
Christina (?) spelled Chris superscript a 8 female
S. 7 male
Geo. Roberts 23
I could not find William in Laurens Co. in 1850
There is another candidate in Abbeville Co. in 1860 who is married to Catherine.